Onset of Action

• 2-3 days
  • Decreased agitation/anxiety
  • Improvements in sleep/appetite
• 1-3 weeks
  • Increased activity and sex drive
  • Improvement in self-care, concentration, memory, and thinking
  • Normalized movements
• 2-4 weeks
  • Reduced depressed mood
  • Experience of pleasure
  • Less hopelessness
  • Decreased suicidal thoughts